| Jul 2, 2026 | | EVP, Chief Commercial Officer | S | Sale | 1,541 | $519.00 | $799.78K | +10.86% | +0.99% | — |
| Jul 2, 2026 | | EVP, Chief Reg. & Quality Off. | S | Sale | 1,500 | $524.99 | $787.49K | +10.86% | +0.99% | — |
| Jul 1, 2026 | | EVP and Chief Legal Officer | S | Sale | 828 | $502.71 | $416.24K | +4.20% | -5.77% | — |
| Jun 26, 2026 | | EVP and CMO | S | Sale | 596 | $482.50 | $287.57K | +2.51% | -6.32% | — |
| Jun 18, 2026 | | EVP and CMO | S | Sale | 1,020 | $462.17 | $471.41K | -6.39% | -13.65% | — |
| Jun 15, 2026 | | EVP and CMO | S | Sale | 4,062 | $450.00 | $1.83M | -5.91% | -15.33% | — |
| Jun 5, 2026 | | EVP and CMO | S | Sale | 1,745 | $450.00 | $785.25K | -18.52% | -24.87% | — |
| Jun 1, 2026 | | EVP and Chief Legal Officer | S | Sale | 828 | $439.91 | $364.25K | -13.60% | -24.21% | — |
| May 29, 2026 | | EVP and CMO | S | Sale | 1,974 | $450.00 | $888.30K | -11.64% | -22.35% | — |
| May 15, 2026 | | EVP, Chief Scientific Officer | S | Sale | 33 | $453.45 | $14.96K | -3.09% | -18.19% | — |
| May 15, 2026 | | EVP and CMO | S | Sale | 1,354 | $453.45 | $613.97K | -3.09% | -18.19% | — |
| May 12, 2026 | | EVP and CMO | S | Sale | 6,988 | $450.00 | $3.14M | +0.72% | -16.87% | — |
| May 4, 2026 | | Director | S | Sale | 318 | $423.73 | $134.75K | +0.35% | -9.51% | — |
| May 1, 2026 | | EVP and Chief Legal Officer | S | Sale | 1,104 | $425.02 | $469.22K | -3.42% | -13.63% | — |
| Apr 1, 2026 | | EVP and Chief Legal Officer | S | Sale | 978 | $449.17 | $439.29K | +5.22% | -11.06% | -17.98% |
| Mar 27, 2026 | | EVP and CMO | S | Sale | 2,329 | $450.95 | $1.05M | +1.63% | -10.88% | -19.23% |
| Mar 13, 2026 | | EVP and CMO | S | Sale | 2,329 | $481.79 | $1.12M | +6.24% | +5.18% | -11.03% |
| Mar 11, 2026 | | EVP, Chief Commercial Officer | S | Sale | 2,633 | $498.42 | $1.31M | +11.40% | +9.47% | -7.42% |
| Mar 4, 2026 | | EVP, Chief Commercial Officer | S | Sale | 2,437 | $475.30 | $1.16M | +9.12% | +11.05% | -13.94% |
| Mar 2, 2026 | | EVP and Chief Legal Officer | S | Sale | 892 | $495.96 | $442.40K | +7.98% | +9.80% | -12.03% |
| Feb 27, 2026 | | CEO & President | S | Sale | 240 | $482.84 | $115.88K | +10.80% | +9.83% | -10.16% |
| Feb 27, 2026 | | EVP and CMO | S | Sale | 2,329 | $480.31 | $1.12M | +10.80% | +9.83% | -10.16% |
| Feb 27, 2026 | | CEO & President | S | Sale | 400 | $479.75 | $191.90K | +10.80% | +9.83% | -10.16% |
| Feb 27, 2026 | | CEO & President | S | Sale | 120 | $481.50 | $57.78K | +10.80% | +9.83% | -10.16% |
| Feb 27, 2026 | | CEO & President | S | Sale | 3,498 | $494.33 | $1.73M | +10.80% | +9.83% | -10.16% |
| Feb 27, 2026 | | CEO & President | S | Sale | 15,580 | $495.38 | $7.72M | +10.80% | +9.83% | -10.16% |
| Feb 27, 2026 | | CEO & President | S | Sale | 5,995 | $496.16 | $2.97M | +10.80% | +9.83% | -10.16% |
| Feb 27, 2026 | | CEO & President | S | Sale | 1,725 | $496.95 | $857.24K | +10.80% | +9.83% | -10.16% |
| Feb 27, 2026 | | CEO & President | S | Sale | 2,520 | $493.29 | $1.24M | +10.80% | +9.83% | -10.16% |
| Feb 27, 2026 | | CEO & President | S | Sale | 949 | $491.30 | $466.24K | +10.80% | +9.83% | -10.16% |
| Feb 27, 2026 | | CEO & President | S | Sale | 2,725 | $490.54 | $1.34M | +10.80% | +9.83% | -10.16% |
| Feb 27, 2026 | | CEO & President | S | Sale | 460 | $489.32 | $225.09K | +10.80% | +9.83% | -10.16% |
| Feb 27, 2026 | | CEO & President | S | Sale | 3,278 | $488.27 | $1.60M | +10.80% | +9.83% | -10.16% |
| Feb 27, 2026 | | CEO & President | S | Sale | 2,510 | $487.13 | $1.22M | +10.80% | +9.83% | -10.16% |
| Feb 26, 2026 | | SVP & Chief Accounting Officer | S | Sale | 357 | $483.36 | $172.56K | +7.70% | +8.94% | -15.15% |
| Feb 25, 2026 | | EVP, Chief Scientific Officer | S | Sale | 620 | $486.35 | $301.54K | +10.35% | +9.75% | -13.36% |
| Feb 25, 2026 | | SVP & Chief Accounting Officer | S | Sale | 223 | $486.35 | $108.46K | +10.35% | +9.75% | -13.36% |
| Feb 25, 2026 | | EVP, Chief Technical Ops. Off. | S | Sale | 668 | $486.35 | $324.88K | +10.35% | +9.75% | -13.36% |
| Feb 25, 2026 | | EVP, Chief Commercial Officer | S | Sale | 2,500 | $486.35 | $1.22M | +10.35% | +9.75% | -13.36% |
| Feb 25, 2026 | | EVP Chief Patient & Ext Af Off | S | Sale | 1,846 | $486.35 | $897.80K | +10.35% | +9.75% | -13.36% |
| Feb 25, 2026 | | EVP, Chief Reg. & Quality Off. | S | Sale | 260 | $486.35 | $126.45K | +10.35% | +9.75% | -13.36% |
| Feb 25, 2026 | | EVP and Chief Legal Officer | S | Sale | 945 | $486.35 | $459.60K | +10.35% | +9.75% | -13.36% |
| Feb 25, 2026 | | EVP, Chief Commercial Officer | S | Sale | 2,410 | $489.00 | $1.18M | +10.35% | +9.75% | -13.36% |
| Feb 19, 2026 | | EVP Chief Patient & Ext Af Off | S | Sale | 2,730 | $465.05 | $1.27M | +3.84% | +8.27% | -12.56% |
| Feb 19, 2026 | | EVP Chief Patient & Ext Af Off | S | Sale | 4,237 | $471.43 | $2.00M | +3.84% | +8.27% | -12.56% |
| Feb 19, 2026 | | EVP Chief Patient & Ext Af Off | S | Sale | 11,712 | $470.54 | $5.51M | +3.84% | +8.27% | -12.56% |
| Feb 19, 2026 | | EVP Chief Patient & Ext Af Off | S | Sale | 7,241 | $469.61 | $3.40M | +3.84% | +8.27% | -12.56% |
| Feb 19, 2026 | | EVP Chief Patient & Ext Af Off | S | Sale | 19,662 | $468.57 | $9.21M | +3.84% | +8.27% | -12.56% |
| Feb 19, 2026 | | EVP Chief Patient & Ext Af Off | S | Sale | 10,263 | $467.75 | $4.80M | +3.84% | +8.27% | -12.56% |
| Feb 19, 2026 | | EVP Chief Patient & Ext Af Off | S | Sale | 1,848 | $465.80 | $860.80K | +3.84% | +8.27% | -12.56% |
| Feb 19, 2026 | | EVP Chief Patient & Ext Af Off | S | Sale | 920 | $463.91 | $426.80K | +3.84% | +8.27% | -12.56% |
| Feb 18, 2026 | | SVP & Chief Accounting Officer | S | Sale | 638 | $473.68 | $302.21K | +3.47% | +7.65% | -9.62% |
| Feb 18, 2026 | | EVP, Chief Reg. & Quality Off. | S | Sale | 368 | $473.68 | $174.31K | +3.47% | +7.65% | -9.62% |
| Feb 18, 2026 | | EVP, Chief Scientific Officer | S | Sale | 1,182 | $473.68 | $559.89K | +3.47% | +7.65% | -9.62% |
| Feb 18, 2026 | | EVP and Chief Legal Officer | S | Sale | 1,244 | $473.68 | $589.26K | +3.47% | +7.65% | -9.62% |
| Feb 18, 2026 | | EVP, Chief Technical Ops. Off. | S | Sale | 817 | $473.68 | $387.00K | +3.47% | +7.65% | -9.62% |
| Feb 17, 2026 | | EVP and Chief Legal Officer | S | Sale | 2,476 | $489.46 | $1.21M | +4.04% | +8.54% | -8.01% |
| Feb 17, 2026 | | EVP, Chief Technical Ops. Off. | S | Sale | 2,031 | $489.46 | $994.09K | +4.04% | +8.54% | -8.01% |
| Feb 17, 2026 | | EVP, Chief Scientific Officer | S | Sale | 2,437 | $489.46 | $1.19M | +4.04% | +8.54% | -8.01% |
| Feb 17, 2026 | | SVP & Chief Accounting Officer | S | Sale | 1,557 | $489.46 | $762.09K | +4.04% | +8.54% | -8.01% |
| Feb 17, 2026 | | EVP, Chief Reg. & Quality Off. | S | Sale | 609 | $489.46 | $298.08K | +4.04% | +8.54% | -8.01% |
| Feb 13, 2026 | | Director | S | Sale | 266 | $500.00 | $133.00K | +5.16% | +8.35% | -6.97% |
| Feb 13, 2026 | | EVP and Chief Legal Officer | S | Sale | 988 | $499.00 | $493.01K | +5.16% | +8.35% | -6.97% |
| Feb 13, 2026 | | EVP, Chief Reg. & Quality Off. | S | Sale | 1,500 | $499.99 | $749.99K | +5.16% | +8.35% | -6.97% |
| Feb 11, 2026 | | EVP, Chief Scientific Officer | S | Sale | 2,021 | $460.43 | $930.53K | -1.76% | +2.81% | -13.59% |
| Feb 11, 2026 | | SVP & Chief Accounting Officer | S | Sale | 1,376 | $460.43 | $633.55K | -1.76% | +2.81% | -13.59% |
| Feb 11, 2026 | | EVP, Chief Technical Ops. Off. | S | Sale | 1,751 | $460.43 | $806.21K | -1.76% | +2.81% | -13.59% |
| Feb 11, 2026 | | EVP and Chief Legal Officer | S | Sale | 1,925 | $460.43 | $886.33K | -1.76% | +2.81% | -13.59% |
| Feb 11, 2026 | | EVP, Chief Reg. & Quality Off. | S | Sale | 466 | $460.43 | $214.56K | -1.76% | +2.81% | -13.59% |
