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Of the 19 tracked institutions holding VRTX, 12 have a 3-year clone track record — 9 of them beat the S&P. Average holder's clone alpha: +3.5pt. It's a gauge of who owns the name, not just how many.
Among the 19 tracked institutional investors we monitor, VRTX (VERTEX PHARMACEUTICALS INC) is held with a combined value of $40.18B across 89,617,831 shares. The largest holder is VANGUARD GROUP INC with a position worth $10.93B (0.16% of their portfolio). Magnetar Financial LLC opened a new position in the most recent quarter. 6 funds increased their holdings. 12 funds reduced their position.
Total Institutional Value
$40.18B
Total Shares Held
89,617,831
Institutional Holders
19
% of Shares Outstanding
35.3%
of 253.81M shares · SEC 2026-04-30
Days to Cover
2.0+7.0%
4.94M shares short · FINRA 2026-06-30
Tracked 13F institutions hold 35.3% of VRTX's shares outstanding. This is a floor: 13F filings arrive on a ~45-day lag and we track only a subset of institutional filers, so true institutional ownership is higher. Shares-outstanding is the latest SEC cover-page figure (as of 2026-04-30), not a live float.
Ranked by estimated dollars moved (share change × implied price). 13F data lags up to 45 days.
0
$0
71
$82.73M
Total Transactions
71
Last 12 months
| Date | Insider | Code | Type | Shares | Value |
|---|---|---|---|---|---|
| Jul 2, 2026 | Duncan McKechnie | S | Sale | 1,541 | $799.78K |
| Jul 2, 2026 | Ourania Tatsis | S | Sale | 1,500 | $787.49K |
| Jul 1, 2026 | Joy Liu | S | Sale | 828 | $416.24K |
| Jun 26, 2026 | Carmen Bozic | S | Sale | 596 | $287.57K |
| Jun 18, 2026 | Carmen Bozic | S | Sale | 1,020 | $471.41K |
| Jun 15, 2026 | Carmen Bozic | S | Sale | 4,062 | $1.83M |
| Jun 5, 2026 | Carmen Bozic | S | Sale | 1,745 | $785.25K |
| Jun 1, 2026 | Joy Liu | S | Sale | 828 | $364.25K |
| May 29, 2026 | Carmen Bozic | S | Sale | 1,974 | $888.30K |
| May 15, 2026 | Mark E. Bunnage | S | Sale | 33 | $14.96K |
Showing 10 of 71 transactions
| # | Fund | Value↓ | Portfolio % | Change |
|---|---|---|---|---|
| 1 | VANGUARD GROUP INC | $10.93B | 0.16% | -0.5% |
| 2 | BlackRock, Inc. | $10.70B | 0.19% | +0.9% |
| 3 | Capital Research Global Investors | $9.43B | 1.46% | +22.0% |
| 4 | STATE STREET CORP | $5.24B | 0.18% | +0.3% |
| 5 | WELLINGTON MANAGEMENT GROUP LLP | $1.43B | 0.27% | -15.9% |
| 6 | FMR LLC | $902.13M | 0.05% | -8.7% |
| 7 | PRICE T ROWE ASSOCIATES INC /MD/ | $785.97M | 0.09% | -22.8% |
| 8 | RENAISSANCE TECHNOLOGIES LLC | $188.30M | 0.29% | -16.5% |
| 9 | CITADEL ADVISORS LLC | $151.51M | 0.11% | -20.6% |
| 10 | ADAGE CAPITAL PARTNERS GP, L.L.C. | $112.52M | 0.17% | -7.5% |
| Member | Type | Date |
|---|---|---|
| Alan Armstrong | Buy | Mar 27, 2026 |
| David J. Taylor | Sell | Jan 29, 2026 |
| David J. Taylor | Buy | Aug 7, 2025 |
| Lisa McClain | Sell |
As of the latest SEC 13F filings, VANGUARD GROUP INC is the largest institutional holder of VRTX with a position worth $10.93B, representing 0.16% of their portfolio. In total, 19 institutional investors hold VRTX with a combined value of $40.18B.
In the most recent quarter, 1 fund opened a new position in VRTX. Additionally, 6 increased their holdings and 12 reduced their positions.
Institutional investors hold $40.18B worth of VRTX stock across 19 positions. The largest institutional holder is VANGUARD GROUP INC with $10.93B in holdings.
A 13F filing is a quarterly report required by the SEC from institutional investment managers with over $100 million in assets. It discloses their holdings in U.S. equities. For VRTX, these filings reveal which major funds are accumulating or reducing positions, providing insights into institutional sentiment.
Get notified when hedge funds change their VRTX positions.
Alpha = the manager's 3-year clone return minus the S&P 500. A skilled roster is a stronger tell than a crowded one — though even skilled managers' edge doesn't reliably survive the 13F disclosure lag. Why →
| Jun 11, 2025 |
| Lisa McClain | Sell | Jun 10, 2025 |
| Jefferson Shreve | Sell | May 12, 2025 |
| Byron Donalds | Sell | Mar 20, 2025 |
| Jefferson Shreve | Buy | Feb 24, 2025 |
Showing 8 of 14. STOCK Act disclosures lag up to 45 days.
Last Close
$477.36
2026-07-24
YTD
+5.6%
68% of 52-week range