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BOSTON, MA · CIK 0001346824
New positions
17
Added to
10
Trimmed
10
Exited
18
RA CAPITAL MANAGEMENT, L.P. (BOSTON, MA) reported a portfolio value of $11.51B across 84 positions in their Q2 2026 SEC 13F filing (period ending 2026-06-30). The top 10 positions account for 60.4% of the portfolio.
Top 30 holdings by portfolio weight. Block width = holding percentage. Green = new/increased, red = reduced, gray = unchanged.
| # | Stock | Value↓ | Weight | Change |
|---|---|---|---|---|
| 1 | ASCENDIS PHARMA A/S | $2.74B | 23.83% | New |
| 2 | PBLSPARABILIS MEDICINES INC | $791.91M | 6.88% | New |
| 3 | RYTMRHYTHM PHARMACEUTICALS INC | $740.22M | 6.43% | - |
| 4 | PCVXVAXCYTE INC | $667.02M | 5.80% | - |
| 5 | SIONSIONNA THERAPEUTICS INC | $435.72M | 3.79% | - |
| 6 | TYRATYRA BIOSCIENCES INC | $389.62M | 3.39% | - |
| 7 | EWTXEDGEWISE THERAPEUTICS INC | $341.00M | 2.96% | -19.5% |
| 8 | NAMSNEWAMSTERDAM PHARMA CO NV | $323.66M | 2.81% | - |
| 9 | COAGHEMAB THERAPEUTICS HOLDINGS | $286.81M | 2.49% | New |
| 10 | SEPNSEPTERNA INC | $234.29M | 2.04% | - |
| Stock | Value | Shares |
|---|---|---|
| ASCENDIS PHARMA A/S | $2.74B | 10,281,496 |
| PBLSPARABILIS MEDICINES INC | $791.91M | 28,933,371 |
| COAGHEMAB THERAPEUTICS HOLDINGS | $286.81M | 7,808,627 |
| ABVXABIVAX SA-ADR | $150.92M | 1,132,557 |
| ORKAORUKA THERAPEUTICS INC | $147.95M | 1,554,597 |
| NTLAINTELLIA THERAPEUTICS INC | $76.60M | 4,526,926 |
| DFTXDEFINIUM THERAPEUTICS INC | $70.56M | 1,500,000 |
| SANASANA BIOTECHNOLOGY INC | $65.44M | 18,750,000 |
| PRLDPRELUDE THERAPEUTICS INC | $34.52M | 6,475,882 |
| QTTBQ32 BIO INC | $29.72M | 2,332,457 |
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