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Of the 14 tracked institutions holding TYRA, 5 have a 3-year clone track record — 5 of them beat the S&P. Average holder's clone alpha: +4.6pt. It's a gauge of who owns the name, not just how many.
Among the 14 tracked institutional investors we monitor, TYRA (TYRA BIOSCIENCES INC) is held with a combined value of $996.38M across 31,484,000 shares. The largest holder is RA CAPITAL MANAGEMENT, L.P. with a position worth $389.62M (3.39% of their portfolio). ADAGE CAPITAL PARTNERS GP, L.L.C. opened a new position in the most recent quarter. 8 funds increased their holdings. 3 funds reduced their position.
Total Institutional Value
$996.38M
Total Shares Held
31,484,000
Institutional Holders
14
Ranked by estimated dollars moved (share change × implied price). 13F data lags up to 45 days.
| # | Fund | Value↓ | Portfolio % | Change |
|---|---|---|---|---|
| 1 | RA CAPITAL MANAGEMENT, L.P. | $389.62M | 3.39% | - |
| 2 | FMR LLC | $284.92M | 0.01% | +15.1% |
| 3 | BlackRock, Inc. | $96.84M | 0.00% | +36.7% |
| 4 | PRICE T ROWE ASSOCIATES INC /MD/ | $88.88M | 0.01% | +182.2% |
| 5 | STATE STREET CORP | $68.36M | 0.00% | +76.0% |
| 6 | VANGUARD GROUP INC | $41.35M | 0.00% | +3.5% |
| 7 | CITADEL ADVISORS LLC | $8.89M | 0.01% | +1707.7% |
| 8 | MILLENNIUM MANAGEMENT LLC | $5.67M | 0.00% | -32.1% |
| 9 | ADAGE CAPITAL PARTNERS GP, L.L.C. | $5.17M | 0.01% | New |
| 10 | Fisher Asset Management, LLC | $1.92M | 0.00% | +109.1% |
As of the latest SEC 13F filings, RA CAPITAL MANAGEMENT, L.P. is the largest institutional holder of TYRA with a position worth $389.62M, representing 3.39% of their portfolio. In total, 14 institutional investors hold TYRA with a combined value of $996.38M.
In the most recent quarter, 1 fund opened a new position in TYRA. Additionally, 8 increased their holdings and 3 reduced their positions.
Institutional investors hold $996.38M worth of TYRA stock across 14 positions. The largest institutional holder is RA CAPITAL MANAGEMENT, L.P. with $389.62M in holdings.
A 13F filing is a quarterly report required by the SEC from institutional investment managers with over $100 million in assets. It discloses their holdings in U.S. equities. For TYRA, these filings reveal which major funds are accumulating or reducing positions, providing insights into institutional sentiment.
Get notified when hedge funds change their TYRA positions.
Alpha = the manager's 3-year clone return minus the S&P 500. A skilled roster is a stronger tell than a crowded one — though even skilled managers' edge doesn't reliably survive the 13F disclosure lag. Why →
| 2026-09-17 |
| 5.8% | 2026-09-17 |
| 6.0% | 2026-08-14 |
| — | 2026-08-14 |
| 5.0% | 2026-07-30 |
SEC Schedule 13D (activist) and 13G (passive) filings for TYRA. Filed when an investor acquires 5%+ ownership.
Last Close
$20.43
2026-10-02
YTD
-23.7%
27% of 52-week range
