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Of the 13 tracked institutions holding TYRA, 5 have a 3-year clone track record — 5 of them beat the S&P. Average holder's clone alpha: +6.3pt. It's a gauge of who owns the name, not just how many.
Among the 13 tracked institutional investors we monitor, TYRA (TYRA BIOSCIENCES INC) is held with a combined value of $992.27M across 26,400,952 shares. The largest holder is RA CAPITAL MANAGEMENT, L.P. with a position worth $467.21M (4.95% of their portfolio). CITADEL ADVISORS LLC opened a new position in the most recent quarter. 7 funds increased their holdings. 2 funds reduced their position.
Total Institutional Value
$992.27M
Total Shares Held
26,400,952
Institutional Holders
13
Ranked by estimated dollars moved (share change × implied price). 13F data lags up to 45 days.
| # | Fund | Value↓ | Portfolio % | Change |
|---|---|---|---|---|
| 1 | RA CAPITAL MANAGEMENT, L.P. | $467.21M | 4.95% | - |
| 2 | FMR LLC | $296.73M | 0.02% | +61570.4% |
| 3 | BlackRock, Inc. | $84.95M | 0.00% | +6.3% |
| 4 | STATE STREET CORP | $46.58M | 0.00% | +62.3% |
| 5 | VANGUARD GROUP INC | $41.35M | 0.00% | +3.5% |
| 6 | PRICE T ROWE ASSOCIATES INC /MD/ | $37.77M | 0.00% | +6732.5% |
| 7 | MILLENNIUM MANAGEMENT LLC | $10.02M | 0.00% | +128.7% |
| 8 | WELLINGTON MANAGEMENT GROUP LLP | $2.96M | 0.00% | -26.0% |
| 9 | Point72 Asset Management, L.P. | $1.49M | 0.00% | -95.6% |
| 10 | AQR CAPITAL MANAGEMENT LLC | $1.13M | 0.00% | +2.8% |
As of the latest SEC 13F filings, RA CAPITAL MANAGEMENT, L.P. is the largest institutional holder of TYRA with a position worth $467.21M, representing 4.95% of their portfolio. In total, 13 institutional investors hold TYRA with a combined value of $992.27M.
In the most recent quarter, 1 fund opened a new position in TYRA. Additionally, 7 increased their holdings and 2 reduced their positions.
Institutional investors hold $992.27M worth of TYRA stock across 13 positions. The largest institutional holder is RA CAPITAL MANAGEMENT, L.P. with $467.21M in holdings.
A 13F filing is a quarterly report required by the SEC from institutional investment managers with over $100 million in assets. It discloses their holdings in U.S. equities. For TYRA, these filings reveal which major funds are accumulating or reducing positions, providing insights into institutional sentiment.
Get notified when hedge funds change their TYRA positions.
Alpha = the manager's 3-year clone return minus the S&P 500. A skilled roster is a stronger tell than a crowded one — though even skilled managers' edge doesn't reliably survive the 13F disclosure lag. Why →
Last Close
$30.63
2026-07-24
YTD
+14.3%
70% of 52-week range
