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Of the 10 tracked institutions holding SEPN, 4 have a 3-year clone track record — 4 of them beat the S&P. Average holder's clone alpha: +4.7pt. It's a gauge of who owns the name, not just how many.
Among the 10 tracked institutional investors we monitor, SEPN (SEPTERNA INC) is held with a combined value of $275.19M across 11,210,372 shares. The largest holder is RA CAPITAL MANAGEMENT, L.P. with a position worth $168.11M (1.78% of their portfolio). 2 funds opened new positions in the most recent quarter. 6 funds increased their holdings. 1 fund reduced its position.
Total Institutional Value
$275.19M
Total Shares Held
11,210,372
Institutional Holders
10
Ranked by estimated dollars moved (share change × implied price). 13F data lags up to 45 days.
| # | Fund | Value↓ | Portfolio % | Change |
|---|---|---|---|---|
| 1 | RA CAPITAL MANAGEMENT, L.P. | $168.11M | 1.78% | - |
| 2 | BlackRock, Inc. | $43.79M | 0.00% | +1.2% |
| 3 | VANGUARD GROUP INC | $42.05M | 0.00% | -0.7% |
| 4 | STATE STREET CORP | $15.17M | 0.00% | +16.9% |
| 5 | MILLENNIUM MANAGEMENT LLC | $2.98M | 0.00% | +15.5% |
| 6 | RENAISSANCE TECHNOLOGIES LLC | $905.93K | 0.00% | New |
| 7 | PRICE T ROWE ASSOCIATES INC /MD/ | $675.00K | 0.00% | +10.3% |
| 8 | ADAGE CAPITAL PARTNERS GP, L.L.C. | $576.72K | 0.00% | New |
| 9 | FMR LLC | $563.41K | 0.00% | +609.0% |
| 10 | AQR CAPITAL MANAGEMENT LLC | $369.46K | 0.00% | +96.5% |
As of the latest SEC 13F filings, RA CAPITAL MANAGEMENT, L.P. is the largest institutional holder of SEPN with a position worth $168.11M, representing 1.78% of their portfolio. In total, 10 institutional investors hold SEPN with a combined value of $275.19M.
In the most recent quarter, 2 funds opened a new position in SEPN. Additionally, 6 increased their holdings and 1 reduced their positions.
Institutional investors hold $275.19M worth of SEPN stock across 10 positions. The largest institutional holder is RA CAPITAL MANAGEMENT, L.P. with $168.11M in holdings.
A 13F filing is a quarterly report required by the SEC from institutional investment managers with over $100 million in assets. It discloses their holdings in U.S. equities. For SEPN, these filings reveal which major funds are accumulating or reducing positions, providing insights into institutional sentiment.
Get notified when hedge funds change their SEPN positions.
Alpha = the manager's 3-year clone return minus the S&P 500. A skilled roster is a stronger tell than a crowded one — though even skilled managers' edge doesn't reliably survive the 13F disclosure lag. Why →
Last Close
$33.10
2026-07-24
YTD
+18.3%
82% of 52-week range