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Of the 10 tracked institutions holding UPB, 4 have a 3-year clone track record — 4 of them beat the S&P. Average holder's clone alpha: +7.2pt. It's a gauge of who owns the name, not just how many.
Among the 10 tracked institutional investors we monitor, UPB (UPSTREAM BIO INC) is held with a combined value of $189.01M across 16,184,590 shares. The largest holder is FMR LLC with a position worth $72.91M. Point72 Asset Management, L.P. opened a new position in the most recent quarter. 6 funds increased their holdings. 3 funds reduced their position.
Total Institutional Value
$189.01M
Total Shares Held
16,184,590
Institutional Holders
10
Ranked by estimated dollars moved (share change × implied price). 13F data lags up to 45 days.
| # | Fund | Value↓ | Portfolio % | Change |
|---|---|---|---|---|
| 1 | FMR LLC | $72.91M | 0.00% | +7.8% |
| 2 | VANGUARD GROUP INC | $64.85M | 0.00% | -2.2% |
| 3 | BlackRock, Inc. | $30.34M | 0.00% | +0.8% |
| 4 | MILLENNIUM MANAGEMENT LLC | $8.44M | 0.00% | +81.2% |
| 5 | STATE STREET CORP | $6.35M | 0.00% | -46.5% |
| 6 | WELLINGTON MANAGEMENT GROUP LLP | $3.08M | 0.00% | -61.7% |
| 7 | Point72 Asset Management, L.P. | $1.60M | 0.00% | New |
| 8 | AQR CAPITAL MANAGEMENT LLC | $649.54K | 0.00% | +136.6% |
| 9 | RENAISSANCE TECHNOLOGIES LLC | $558.90K | 0.00% | +278.7% |
| 10 | PRICE T ROWE ASSOCIATES INC /MD/ | $238.00K | 0.00% | +34.6% |
As of the latest SEC 13F filings, FMR LLC is the largest institutional holder of UPB with a position worth $72.91M, representing 0.00% of their portfolio. In total, 10 institutional investors hold UPB with a combined value of $189.01M.
In the most recent quarter, 1 fund opened a new position in UPB. Additionally, 6 increased their holdings and 3 reduced their positions.
Institutional investors hold $189.01M worth of UPB stock across 10 positions. The largest institutional holder is FMR LLC with $72.91M in holdings.
A 13F filing is a quarterly report required by the SEC from institutional investment managers with over $100 million in assets. It discloses their holdings in U.S. equities. For UPB, these filings reveal which major funds are accumulating or reducing positions, providing insights into institutional sentiment.
Get notified when hedge funds change their UPB positions.
Alpha = the manager's 3-year clone return minus the S&P 500. A skilled roster is a stronger tell than a crowded one — though even skilled managers' edge doesn't reliably survive the 13F disclosure lag. Why →
Last Close
$6.41
2026-07-24
YTD
-76.3%
2% of 52-week range