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Of the 16 tracked institutions holding TWST, 8 have a 3-year clone track record — 5 of them beat the S&P. Average holder's clone alpha: +1.4pt. It's a gauge of who owns the name, not just how many.
Among the 16 tracked institutional investors we monitor, TWST (TWIST BIOSCIENCE CORP) is held with a combined value of $2.77B across 30,921,185 shares. The largest holder is BlackRock, Inc. with a position worth $600.19M. 4 funds opened new positions in the most recent quarter. 6 funds increased their holdings. 6 funds reduced their position.
Total Institutional Value
$2.77B
Total Shares Held
30,921,185
Institutional Holders
16
Ranked by estimated dollars moved (share change × implied price). 13F data lags up to 45 days.
| # | Fund | Value↓ | Portfolio % | Change |
|---|---|---|---|---|
| 1 | BlackRock, Inc. | $600.19M | 0.01% | +5.0% |
| 2 | FMR LLC | $483.85M | 0.02% | +148.8% |
| 3 | ARK Investment Management LLC | $468.08M | 3.04% | -28.3% |
| 4 | PRICE T ROWE ASSOCIATES INC /MD/ | $373.93M | 0.04% | +5069.8% |
| 5 | STATE STREET CORP | $332.56M | 0.01% | -11.9% |
| 6 | VANGUARD GROUP INC | $183.22M | 0.00% | +0.1% |
| 7 | BAILLIE GIFFORD & CO | $111.81M | 0.10% | -10.6% |
| 8 | CITADEL ADVISORS LLC | $88.69M | 0.05% | -29.4% |
| 9 | WELLINGTON MANAGEMENT GROUP LLP | $58.47M | 0.01% | -23.1% |
| 10 | MILLENNIUM MANAGEMENT LLC | $35.71M | 0.02% | -1.0% |
As of the latest SEC 13F filings, BlackRock, Inc. is the largest institutional holder of TWST with a position worth $600.19M, representing 0.01% of their portfolio. In total, 16 institutional investors hold TWST with a combined value of $2.77B.
In the most recent quarter, 4 funds opened a new position in TWST. Additionally, 6 increased their holdings and 6 reduced their positions.
Institutional investors hold $2.77B worth of TWST stock across 16 positions. The largest institutional holder is BlackRock, Inc. with $600.19M in holdings.
A 13F filing is a quarterly report required by the SEC from institutional investment managers with over $100 million in assets. It discloses their holdings in U.S. equities. For TWST, these filings reveal which major funds are accumulating or reducing positions, providing insights into institutional sentiment.
Get notified when hedge funds change their TWST positions.
Alpha = the manager's 3-year clone return minus the S&P 500. A skilled roster is a stronger tell than a crowded one — though even skilled managers' edge doesn't reliably survive the 13F disclosure lag. Why →
| 2026-09-08 |
| 4.2% | 2026-08-14 |
| 7.3% | 2026-08-14 |
| 5.8% | 2026-08-14 |
| 7.7% | 2026-08-13 |
| 3.5% | 2026-08-11 |
| 7.6% | 2026-08-06 |
SEC Schedule 13D (activist) and 13G (passive) filings for TWST. Filed when an investor acquires 5%+ ownership.
Last Close
$188.67
2026-10-02
YTD
+482.5%
97% of 52-week range
