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NEW YORK, NY · CIK 0001263508
Portfolio Value
$13.84B
Positions
93
New
12
Increased
14
Decreased
6
Sold Out
10
BAKER BROS. ADVISORS LP (NEW YORK, NY) reported a portfolio value of $13.84B across 93 positions in their Q3 2025 SEC 13F filing (period ending 2025-09-30). The top 10 positions account for 79.1% of the portfolio.
Top 30 holdings by portfolio weight. Block width = holding percentage. Green = new/increased, red = reduced, gray = unchanged.
| # | Stock | Value↓ | Weight | Change |
|---|---|---|---|---|
| 1 | ONCBeOne Medicines Ltd. | $3.00B | 21.66% | - |
| 2 | INCYIncyte Corporation | $2.61B | 18.84% | +0.0% |
| 3 | MDGLMadrigal Pharmaceuticals, Inc. | $982.31M | 7.10% | +8.4% |
| 4 | INSMInsmed Incorporated | $965.37M | 6.98% | -13.1% |
| 5 | ACADACADIA Pharmaceuticals Inc. | $915.42M | 6.61% | - |
| 6 | SMMTSummit Therapeutics Inc. | $696.72M | 5.03% | - |
| 7 | RYTMRhythm Pharmaceuticals, Inc. | $566.00M | 4.09% | - |
| 8 | RVMDRevolution Medicines, Inc. | $441.57M | 3.19% | +1.0% |
| 9 | CELCCelcuity Inc. | $391.04M | 2.83% | +45.2% |
| 10 | KYMRKymera Therapeutics, Inc. | $376.47M | 2.72% | - |
| Stock | Value | Shares |
|---|---|---|
| ABVXAbivax S.A. | $74.36M | 875,796 |
| CELC 2.75 08/01/31Celcuity Inc. | $40.91M | 30,750,000 |
| IONSIonis Pharmaceuticals, Inc. | $37.08M | 566,798 |
| RNAGBPAvidity Biosciences, Inc. | $27.23M | 625,000 |
| VKTXViking Therapeutics, Inc. | $9.62M | 366,083 |
| PHVSPharvaris N.V. | $9.36M | 375,000 |
| HRTXHeron Therapeutics, Inc. | $5.36M | 4,251,951 |
| MBXMBX Biosciences, Inc. | $4.86M | 277,777 |
| VTYXUSDVentyx Biosciences, Inc. | $3.18M | 1,023,130 |
| LBRXLB Pharmaceuticals Inc. | $3.16M | 200,000 |
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