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Of the 8 tracked institutions holding GPCR, 3 have a 3-year clone track record — 3 of them beat the S&P. Average holder's clone alpha: +3.4pt. It's a gauge of who owns the name, not just how many.
Alpha = the manager's 3-year clone return minus the S&P 500. A skilled roster is a stronger tell than a crowded one — though even skilled managers' edge doesn't reliably survive the 13F disclosure lag. Why →
Among the 8 tracked institutional investors we monitor, GPCR (STRUCTURE THERAPEUTICS INC) is held with a combined value of $976.16M across 18,188,146 shares. The largest holder is FMR LLC with a position worth $419.18M (0.02% of their portfolio). ADAGE CAPITAL PARTNERS GP, L.L.C. opened a new position in the most recent quarter. 2 funds increased their holdings. 4 funds reduced their position.
Total Institutional Value
$976.16M
Total Shares Held
18,188,146
Institutional Holders
8
Ranked by estimated dollars moved (share change × implied price). 13F data lags up to 45 days.
| # | Fund | Value↓ | Portfolio % | Change |
|---|---|---|---|---|
| 1 | FMR LLC | $419.18M | 0.02% | -7.1% |
| 2 | WELLINGTON MANAGEMENT GROUP LLP | $396.05M | 0.07% | +1.6% |
| 3 | BAKER BROS. ADVISORS LP | $76.88M | 0.39% | - |
| 4 | PRICE T ROWE ASSOCIATES INC /MD/ | $45.38M | 0.00% | -57.7% |
| 5 | BlackRock, Inc. | $27.43M | 0.00% | +15.7% |
| 6 | MILLENNIUM MANAGEMENT LLC | $4.81M | 0.00% | -47.0% |
| 7 | ADAGE CAPITAL PARTNERS GP, L.L.C. | $4.03M | 0.01% | New |
| 8 | STATE STREET CORP | $2.40M | 0.00% | -6.2% |
SEC Schedule 13D (activist) and 13G (passive) filings for GPCR. Filed when an investor acquires 5%+ ownership.
As of the latest SEC 13F filings, FMR LLC is the largest institutional holder of GPCR with a position worth $419.18M, representing 0.02% of their portfolio. In total, 8 institutional investors hold GPCR with a combined value of $976.16M.
In the most recent quarter, 1 fund opened a new position in GPCR. Additionally, 2 increased their holdings and 4 reduced their positions.
Institutional investors hold $976.16M worth of GPCR stock across 8 positions. The largest institutional holder is FMR LLC with $419.18M in holdings.
A 13F filing is a quarterly report required by the SEC from institutional investment managers with over $100 million in assets. It discloses their holdings in U.S. equities. For GPCR, these filings reveal which major funds are accumulating or reducing positions, providing insights into institutional sentiment.
Get notified when hedge funds change their GPCR positions.
Last Close
$21.08
2026-10-16
YTD
-69.1%
0% of 52-week range