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BAKER BROS. ADVISORS LP

NEW YORK, NY · CIK 0001263508

Portfolio Value: $12.22B
Positions: 119
Period: 2017-03-31
Filed: 2017-05-15
Q4 2025Q3 2025Q2 2025Q1 2025Q4 2024Q3 2024Q2 2024Q1 2024Q4 2023Q3 2023Q2 2023Q1 2023Q4 2022Q3 2022Q2 2022Q1 2022Q4 2021Q3 2021Q2 2021Q1 2021Q4 2020Q3 2020Q2 2020Q1 2020Q4 2019Q3 2019Q2 2019Q1 2019Q4 2018Q3 2018Q2 2018Q1 2018Q4 2017Q3 2017Q2 2017Q1 2017Q4 2016Q3 2016Q2 2016Q1 2016Q4 2015Q3 2015Q2 2015Q1 2015Q4 2014

Portfolio Value

$12.22B

Positions

119

New

6

Increased

21

Decreased

10

Sold Out

93

BAKER BROS. ADVISORS LP Q1 2017 13F Filing Summary

BAKER BROS. ADVISORS LP (NEW YORK, NY) reported a portfolio value of $12.22B across 119 positions in their Q1 2017 SEC 13F filing (period ending 2017-03-31). Top holdings include INCY ($4.56B), SE ($2.87B), ACAD ($887.68M). The top 10 positions account for 86.7% of the portfolio. This quarter saw 6 new positions, 21 increases, 10 reductions, 93 complete exits. Notable new buys: NVAX ($48.55M), ANAB ($4.16M), THCH ($2.20M). Notable exits: ATI, ATI, Derma Sciences, Inc..

All Holdings

#StockValue↓WeightChange
1
INCYIncyte Corporation
COM
$4.56B
37.31%
+45.2%
2
SESeattle Genetics, Inc.
COM
$2.87B
23.51%
+0.0%
3
ACADACADIA Pharmaceuticals Inc.
COM
$887.68M
7.26%
-
4
Alexion Pharmaceuticals, Inc.
COM
$793.41M
6.49%
+0.0%
5
THCHGenomic Health, Inc.
COM
$433.65M
3.55%
+0.0%
6
BMRNBioMarin Pharmaceutical Inc.
COM
$421.91M
3.45%
-
7
DBV Technologies S.A.
SPONSORED ADR
$194.05M
1.59%
-
8
Aquinox Pharmaceuticals, Inc.
COM
$182.49M
1.49%
+3.8%
9
ONCBeiGene, Ltd.
SPONSORED ADR
$134.47M
1.10%
-
10
Achaogen, Inc.
COM
$115.61M
0.95%
-
11
BCRXBioCryst Pharmaceuticals, Inc.
COM
$98.42M
0.81%
+6.9%
12
BMRNBioMarin Pharmaceutical Inc.
NOTE 1.875% 4/23/2017
$95.97M
0.79%
-
13
PPLAdvanced Accelerator Applications S.A.
SPONSORED ADS
$88.56M
0.72%
+2.5%
14
Invitae Corporation
COM
$80.61M
0.66%
-
15
AMRNAmarin Corporation plc
SPONSORED ADR NEW
$72.50M
0.59%
+2.2%
16
PARSpark Therapeutics, Inc.
COM
$70.32M
0.58%
-
17
THCHAcorda Therapeutics, Inc.
COM
$69.34M
0.57%
-
18
Bellicum Pharmaceuticals, Inc.
COM
$62.10M
0.51%
+3.4%
19
CERSCerus Corporation
COM
$58.09M
0.48%
-
20
EXELExelixis, Inc.
COM
$56.42M
0.46%
-13.3%
21
NVAXNovavax, Inc.
Note 3.75% 2/1/2023 ADDED
$48.55M
0.40%
New
22
HRTXHeron Therapeutics, Inc.
COM
$41.75M
0.34%
+16.8%
23
NBIXNeurocrine Biosciences, Inc.
COM
$38.77M
0.32%
-
24
AveXis, Inc.
COM
$38.02M
0.31%
+58.6%
25
ASNDAscendis Pharma A/S
SPONSORED ADR
$37.84M
0.31%
+32.1%
26
Versartis, Inc.
COM
$35.45M
0.29%
-13.5%
27
BLUEbluebird bio, Inc.
COM
$31.95M
0.26%
-
28
PRGProgenics Pharmaceuticals, Inc.
COM
$29.74M
0.24%
-
29
THCHAcorda Therapeutics, Inc.
NOTE 1.75% 6/15/2021
$29.70M
0.24%
-
30
MRUSMerus N.V.
COM
$28.29M
0.23%
-
31
Idera Pharmaceuticals, Inc.
COM NEW
$25.41M
0.21%
+0.1%
32
SGMOSangamo Therapeutics, Inc.
COM
$23.56M
0.19%
+11.7%
33
GLPGGalapagos NV
SPONSORED ADR
$22.40M
0.18%
-
34
XNCRXencor, Inc.
COM
$20.86M
0.17%
-
35
HALOHalozyme Therapeutics, Inc.
COM
$18.03M
0.15%
-
36
NeuroDerm Ltd.
ORD SHS
$15.18M
0.12%
-
37
NTLAIntellia Therapeutics, Inc.
COM
$14.96M
0.12%
-
38
SAGESage Therapeutics, Inc.
COM
$14.81M
0.12%
-
39
THCHAimmune Therapeutics, Inc.
COM
$14.64M
0.12%
-
40
ARRYArray BioPharma Inc.
COM
$14.18M
0.12%
-38.7%
41
Dermira, Inc.
COM
$14.17M
0.12%
+27.3%
42
BMRNBioMarin Pharmaceutical Inc.
NOTE 0.75% 10/15/2018
$13.83M
0.11%
-
43
AERIEURAerie Pharmaceuticals, Inc.
COM
$13.58M
0.11%
-
44
Aegerion Pharmaceuticals, Inc.
NOTE 2.0% 8/15/2019
$13.24M
0.11%
-37.7%
45
Foamix Pharmaceuticals Ltd.
SHS
$12.21M
0.10%
-
46
ATIMirati Therapeutics, Inc.
COM
$11.80M
0.10%
-
47
ImmunoGen, Inc.
COM
$11.67M
0.10%
-
48
La Jolla Pharmaceutical Company
COM PAR $.0001 2
$11.32M
0.09%
+2658.1%
49
CPRXCatalyst Pharmaceuticals, Inc.
COM
$9.95M
0.08%
-
50
APGIntra-Cellular Therapies, Inc.
COM
$9.90M
0.08%
-
Showing 1-50 of 119

Position Changes

StockValueShares
NVAXNovavax, Inc.
$48.55M108,500,000
ANABAnaptysBio, Inc.
$4.16M150,000
THCHJounce Therapeutics, Inc.
$2.20M100,000
NODKTonix Pharmaceuticals Holdings Corp.
$2.10M449,500
ATIBioverativ Inc.
$449.00K8,249
ATIBioPharmX Corporation
$191.00K377,295